Combined with potent antioxidants, CLINICAL 1% Retinol Treatment is a specially formulated light lotion that absorbs quickly and goes to work immediately to enhance hydration and diminish the appearance of wrinkles, fine lines, and uneven skin tones. Licorice, oat extract and other soothing ingredients help to calm redness.

All Paula’s Choice products are 100% fragrance free, clinically proven to be non-irritating, and never tested on animals.

2022 NewBeauty Award, Best 1% Retinol Serum

Goes to work immediately to visibly refine pore size and diminish the appearance of wrinkles, fine lines and uneven skin tone. The light lotion formula is supplemented with nourishing licorice extract, oat extract and other soothing plant extracts to calm skin and ease redness. You’ll be amazed at how much younger-looking, firmer, and radiant your skin will look and feel.

Limit initial use to three times per week; gradually increase frequency to every other night, then finally each evening as tolerated. Apply a pea-sized amount after cleansing and toning. Carefully avoid the lips, eyes (including eyelids) and corners of the eyes. Can be used on the perimeter of the orbital bone if desired. To minimize irritation, try combining with 2-3 drops of Resist Moisture Renewal Oil Booster.

Note: Some people may experience a delayed sensitized reaction to 1% retinol. Do not assume that if no reaction is seen after a few applications that you can apply this product more frequently. Pay close attention to how your skin responds and adjust usage accordingly.

If sensitization occurs (redness, flaking, tenderness, or drying of skin), reduce frequency of use or mix one pump of the Clinical 1% Retinol Treatment with your favorite Paula’s Choice serum or PM moisturizer. If sensitization persists, discontinue use. Protect skin daily with sunscreen rated SPF 30 or greater.

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Journal of Drugs in Dermatology, March 2015, issue 3, pages 271-280
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Journal of Cosmetic Dermatology, December 2008, issue 4, pages 281-289
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American Journal of Clinical Dermatology, 2003, issue 2, pages 107-129
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Key Ingredients
Salix Alba Extract, Dipotassium Glycyrrhizate, Arctium Lappa, Phytosterol, Cetyl Esters, Tetrahexyldecyl Ascorbate, Retinol, Glycine Soja Sterols, Glycerin, Sodium Hyaluronate, Allantoin, Avena Sativa, Palmitoyl Tetrapeptide-7, Lecithin, Dimethicone, Palmitoyl Tripeptide-1, Laurdimonium Hydroxypropyl Hydrolyzed Soy Protein, Glycyrrhiza Glabra, Ceramide NS, Palmitoyl Hexapeptide-12, Tocopheryl Acetate

Product Ingredients
Water (Aqua), Dimethicone (skin-softening), Glycerin (skin-replenishing), Butylene Glycol (hydrating), Isononyl Isononanoate (emollient), Castor Isostearate Succinate (skin-softening ), Glyceryl Stearate (texture enhancer), C12-15 Alkyl Benzoate (emollient), Dimethicone Crosspolymer (texture enhancer), PEG-33 (stabilizer), Polysorbate 20 (texture enhancer), Behenyl Alcohol (texture enhancer), PEG-100 Stearate (texture enhancer), Pentaerythrityl Tetraisostearate (stabilizer), Polymethylsilsesquioxane (texture enhancer), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Retinol (skin-restoring), Ceramide NG (skin-replenishing) , Palmitoyl Tetrapeptide-7 (skin-restoring), Palmitoyl Hexapeptide-12 (skin-restoring), Sodium Hyaluronate (skin-replenishing ), Dipotassium Glycyrrhizate (antioxidant plant extracts/skin-soothing), Glycyrrhiza Glabra Root Extract (licorice extract/antioxidant/skin-soothing), Avena Sativa Kernel Extract (oat extract/antioxidant/skin-soothing), Arctium Lappa Root Extract (burdock extract/antioxidant/skin-soothing), Salix Alba Bark Extract (willow bark extract/antioxidant/skin-soothing), Glycine Soja Sterols (antioxidant/skin-softening ), Lecithin (skin-restoring), Allantoin (skin-soothing), Tocopheryl Acetate (vitamin E/antioxidant), Hydrolyzed Soy Protein (antioxidant/skin-softening), Sorbitan Laurate (texture enhancer), Acetyl Dipeptide-1 Cetyl Ester (skin-soothing), Disodium EDTA (stabilizer), Hydroxyethylcellulose (texture enhancer), Palmitoyl Tripeptide-1 (skin-restoring), Sodium Hydroxide (pH adjuster), Tribehenin (emollient), Caprylyl Glycol (skin-softening), Ethylhexylglycerin (skin-softening), Pentylene Glycol (hydrating), PEG-75 Shea Butter Glycerides (emollient), PPG-12/SMDI Copolymer (stabilizer), PEG-10 Phytosterol (fatty acid-based emollient), PEG-8 Dimethicone (skin-softening), PEG-14 (texture enhancer), Magnesium Aluminum Silicate (texture enhancer), Arachidyl Glucoside (texture enhancer), Arachidyl Alcohol (texture enhancer), Sclerotium Gum (texture enhancer), Carbomer (gel-based texture enhancer), Phenoxyethanol (preservative), Benzoic Acid (preservative).